Nonsurgical Metabolic Control
The concept of metabolic control is to control the body's natural metabolism -- to "reengineer" metabolic pathways within the body to achieve a desired response.
The EndoBarrier™ Gastrointestinal Liner offers metabolic control by influencing how food moves through the digestive system, similar to the effect of gastric bypass surgery. However, the EndoBarrier Gastrointestinal Liner is a nonsurgical approach, which makes it unique among other highly effective obesity interventions.
Eighty-four percent of patients immediately resolve their type 2 diabetes with gastric bypass surgery, a phenomenon found to occur as a primary, specific, and direct effect of this surgery -- not secondary to the weight loss. The same metabolic control of type 2 diabetes documented after gastric bypass surgery may be realized with the EndoBarrier Gastrointestinal Liner.
| Mechanism of Action | Roux-en-Y | Gastric Banding | EndoBarrier |
|---|---|---|---|
| Restriction of stomach volume | X | X | |
| Increased resistance to gastric emptying | X | ||
| Bypass of distal stomach | X | ||
| Bypass of duodenum/jejunum | X | X | |
| Exposure of jejunum to undigested food | X | X |
The EndoBarrier Gastrointestinal Liner is a noninvasive, nonsurgical approach that may provide benefits similar to those achieved with invasive surgical procedures.